![]() Bone responds in a variety of ways to vitamin, mineral, and hormone deficiencies or excesses. The process of bone repair and the incorporation of heavy metals and rare earths (including radioisotopes) in the adult skeleton attest to its dynamic nature. For a consideration of various aspects of development, maintenance, and repair of the skeleton, reference can be made to Kimmel and Jee (1982), Kincaid and Van Sickle (1983), Jurvelin et al. In the living body the skeleton is composed of a changing, actively metabolizing tissue that may be altered in shape, size, and position by mechanical or biochemical demands. It functions as a storehouse for minerals and as a site for fat storage and blood cell formation. The skeleton serves for support and protection while providing levers for muscular action.
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